000 02269cmm a2200241 a 4500
001 46843
003 IN-BdCUP
005 20230426175601.0
008 230426s2023 u eng
020 _a9781482221350
040 _beng
_cIN-BdCUP
041 _aeng
082 _a615.700
_bB736
100 _aBoroujerdi, Mehdi
_eAuthor
245 0 _aPharmacokinetics and toxicokinetics /
_cMehdi Boroujerdi, College of Health Sciences - School of Pharmacy, University of Massachusetts Lowell, Lowell, Massachusetts USA
260 _aBoca Raton, Florida :
_bCRC Press :;Taylor & Francis Group,
_c[2015];©2015
300 _a1 online resource
505 _achapter 1. The influence of routes of administration on ADME -- chapter 2. Mechanisms of absorption and permeation of xenobiotics -- chapter 3. In Vivo distribution of xenobiotics -- chapter 4. Elimination rate, clearance, and the theoretical models -- chapter 5. Renal excretion of xenobiotics and estimation of related PK/TK parameters and constants -- chapter 6. Biotransformation of xenobiotics -- chapter 7. Kinetics of In Vitro metabolism : assimilation of intrinsic clearance in hepatic clearance -- chapter 8. Pharmaceutical, biopharmaceutical, and physiological factors influencing oral absorption : mechanistic absorption models -- chapter 9. Mathematical modeling in pharmacokinetics and toxicokinetics -- chapter 10. PK/TK analysis of instantaneous exposure to xenobiotics (single bolus injection) -- chapter 11. PK/TK analysis of continuous zero-order exposure to xenobiotics (intravenous infusion) -- chapter 12. PK/TK analysis of xenobiotics absorbed via an extravascular route of administration (oral administration) -- chapter 13. PK/TK of xenobiotics absorbed through the skin (transdermal absorption) -- chapter 14. PK/TK analysis of multiple dosing -- chapter 15. Bioavailability, bioequivalence, and biosimilar evaluations -- chapter 16. Preclinical PK/TK and clinical trials -- chapter 17. Population pharmacokinetics/toxicokinetics -- chapter 18. Quantitative extrapolation interspecies scaling/low dose extrapolation
650 _aPharmacokinetics
650 _aXenobiotics
856 _3Electronic Book Resource
_uhttps://www.taylorfrancis.com/books/9781482221350
942 _2ddc
_cE
999 _c48853
_d48853