000			02828nam a2200229Ia 4500
001			19581
003			IN-BdCUP
005			20240620150311.0
008			230413s2023 000 0 eng
020			_a9781439875940
040			_beng _cIN-BdCUP
041			_aeng
082			_a547.78 _bMAR
245		0	_aCarbohydrate chemistry : _bproven synthetic methods / _cGijsbert Van Der Marel and Jeroen Codee (Ed.)
260			_aNew York : _bCRC Press, _c2014.
300			_axxxix, 293 p. ; _c24 cm.
520			_aThe second volume in the series Carbohydrate Proven Synthetic Methods, Volume 2 offers a collection of synthetic procedures valuable to the practice of synthetic carbohydrate chemistry. The series takes an important and unique approach in that all described procedures have been independently verified as reliable and reproducible. With editors and contributors who are highly respected scientists in the field, this book provides a widely useful reference for both researchers and students, exploring carbohydrate chemistry from both academic and industrial points of view. The book begins with an introductory section that offers tricks and tips collected by the series editor from many years of experience working in carbohydrate laboratories. The subsequent chapters present detailed protocols on both specific synthetic transformations and the preparation of common synthetic intermediates, with figures to aid in comprehension. Procedures are described for regioselective benzylidene ring opening reactions, oxidation reactions to provide uronic acids, stereoselective alpha-glucosylation reactions, and more. Protocols for synthetic intermediates of general utility include 3,4,6-tri- O -acetyl-d-galactal, phenyl 4,6- O -benzylidene-1-thio-α-d-mannopyranoside, 1,2-anhydro-3,4,6-tri- O -benzyl-β-d-mannopyranoside, and methyl N -acetylneuraminic acid, among many others. Each chapter presents in-depth experimental descriptions for the reported procedures, including reaction setup, reaction conditions, work-up procedures, and purification protocols. The chapters also provide detailed characterization of all products and intermediates as well as copies of the 1H NMR and 13C NMR of the described products and intermediates to indicate the purity of the obtained materials and to serve as a valuable reference for future practitioners. This book provides an important starting point to reliably access synthetic carbohydrate materials and as such offers a valuable resource for the synthetic organic chemistry community. Through the streamlined access of well-defined products it provides a thrust to the rapidly growing field of chemical glycobiology.
650			_aCarbohydrate chemistry
700			_aMarel, Gijsbert Van Der. _eEditor
700			_aCodee, Jeroen _eEditor
942			_2ddc _cBK
999			_c15700 _d15700