Cancer Evolution / (Record no. 31432)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02613nam a2200337Ia 4500 |
| 001 - CONTROL NUMBER | |
| control field | 42445 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | IN-BdCUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20230421155220.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230413s2023 000 0 eng |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1621821439 |
| 040 ## - CATALOGING SOURCE | |
| Language of cataloging | eng |
| Transcribing agency | IN-BdCUP |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.994 |
| Item number | SWA |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Swanton, Charles |
| Relator term | Editor |
| 245 #0 - TITLE STATEMENT | |
| Title | Cancer Evolution / |
| Statement of responsibility, etc. | Swanton, Charles (Ed.); Bardelli, Alberto (Ed.); Polyak, Kornelia (Ed.) & Shah, Sohrab P. (Ed.) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | New York : |
| Name of publisher, distributor, etc. | Cold Spring Harbor Laboratory Press, |
| Date of publication, distribution, etc. | 2017. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | vii, 304p. ; |
| Dimensions | 27 cm. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetics |
| Topical term or geographic name entry element | Evolution |
| Topical term or geographic name entry element | Life sciences |
| Topical term or geographic name entry element | Oncology |
| Topical term or geographic name entry element | Medical |
| Topical term or geographic name entry element | Cancer--Research |
| Topical term or geographic name entry element | Cancer |
| Topical term or geographic name entry element | Cancer--Treatment |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bardelli, Alberto |
| Relator term | Editor |
| Personal name | Polyak, Kornelia |
| Relator term | Editor |
| Personal name | Shah, Sohrab P. (Ed.) |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Book |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Source of acquisition | Cost, normal purchase price | Bill number | Total checkouts | Full call number | Barcode | Date last seen | Actual Cost, replacement price | Bill Date | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | Ranganathan Library | Ranganathan Library | 19/06/2020 | Data Entry Backlog | 6224.00 | SIVB-30-08617 | 616.994 SWA | 039026 | 13/04/2023 | 4045.60 | 11/02/2020 | Book |