Pharmacokinetics and toxicokinetics /

Boroujerdi, Mehdi

Pharmacokinetics and toxicokinetics / Mehdi Boroujerdi, College of Health Sciences - School of Pharmacy, University of Massachusetts Lowell, Lowell, Massachusetts USA - Boca Raton, Florida : CRC Press :;Taylor & Francis Group, [2015];©2015 - 1 online resource

chapter 1. The influence of routes of administration on ADME -- chapter 2. Mechanisms of absorption and permeation of xenobiotics -- chapter 3. In Vivo distribution of xenobiotics -- chapter 4. Elimination rate, clearance, and the theoretical models -- chapter 5. Renal excretion of xenobiotics and estimation of related PK/TK parameters and constants -- chapter 6. Biotransformation of xenobiotics -- chapter 7. Kinetics of In Vitro metabolism : assimilation of intrinsic clearance in hepatic clearance -- chapter 8. Pharmaceutical, biopharmaceutical, and physiological factors influencing oral absorption : mechanistic absorption models -- chapter 9. Mathematical modeling in pharmacokinetics and toxicokinetics -- chapter 10. PK/TK analysis of instantaneous exposure to xenobiotics (single bolus injection) -- chapter 11. PK/TK analysis of continuous zero-order exposure to xenobiotics (intravenous infusion) -- chapter 12. PK/TK analysis of xenobiotics absorbed via an extravascular route of administration (oral administration) -- chapter 13. PK/TK of xenobiotics absorbed through the skin (transdermal absorption) -- chapter 14. PK/TK analysis of multiple dosing -- chapter 15. Bioavailability, bioequivalence, and biosimilar evaluations -- chapter 16. Preclinical PK/TK and clinical trials -- chapter 17. Population pharmacokinetics/toxicokinetics -- chapter 18. Quantitative extrapolation interspecies scaling/low dose extrapolation

9781482221350


Pharmacokinetics
Xenobiotics

615.700 / B736
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